Description

Position Summary

The laboratory of Associate Professor Scott Canfield at Indiana University School of Medicine - Terre Haute, is seeking a talented and highly motivated Postdoctoral Researcher to join a pioneering research project within the framework of our recently NIH funded Micro physiological Systems to Advance Precision Medicine for Alzheimer's Disease and Related Dementias ( MAP -AD). This innovative and multidisciplinary project aims to develop brain oganoids derived from human iPSCs- to study vascular dysfunction in Alzheimer's disease and related dementias. Project Overview Leveraging newly developed brain organoid models, this project will: Utilize human iPSC lines from AD patients to develop multiple tiered brain organoid models. Investigate vascular dysfunction and neuroinflammation in three-dimensional cellular models, Utilize cutting-edge techniques including confocal microscopy, physiological and shear flow, and artificial intelligence systems to enable functional phenotyping of the MAP -AD models. Improve translational micro physiological systems models to improve AD outcomes.

IUSM is committed to being a welcoming campus community and we seek candidates whose research, teaching, and community engagement efforts contribute to robust learning and working environments for all students, staff, and faculty. We invite individuals who will join us in our mission to improve health equity and well-being for all throughout the state of Indiana.

Basic Qualifications

We are looking for candidates with an interest in iPSC and blood-brain barrier research. Ideal candidates will have: 1.A PhD in the life sciences 2.A solid background in cell culture and tissue engineering approaches 3.Knowledge in Neuroscience and Stem Cell Research 4.A collaborative spirit and the ability to thrive in an interdisciplinary research environment. 5.Proven scientific writing and publishing experience. 6.A strong commitment to building a career in brain barriers biology. 7.Excellent communication skills in English (spoken and written)

Department Contact for Questions

Scott Canfield, PhD
sccanfie@iu.edu